![]() During apheresis, blood is removed from a central line or through a needle in one arm, the stem cells are collected, and the remaining blood components are returned through the central line or through a needle in the other arm. ![]() Stem cells are collected from circulating blood in an outpatient setting using a procedure called apheresis. How cells are collected for stem cell transplant Peripheral blood stem cell transplant These patients face the same odds of developing graft-versus-host disease (GVHD) as high-intensity transplant recipients. Although reduced-intensity transplants spare patients the intensive doses of chemotherapy, there is nothing reduced about the risks. It also creates some space in the marrow for the new stem cells. The chemotherapy suppresses the immune system to prevent graft rejection. Non-myeloablative (reduced-intensity) transplant uses a lower dose of chemotherapy and no radiation, followed by an infusion of disease-fighting stem cells from a donor whose tissue type matches your own. In cases when a patient’s own stem cells are healthy enough, they are transplanted (autologous transplant) otherwise, transplanted cells are from a donor (allogeneic transplant). Patients receive an infusion of new stem cells to rebuild blood and the immune system. In this process, bone marrow/stem cells are also destroyed. Myeloablative (high-intensity) stem cell transplant uses high doses of chemotherapy and may use radiation therapy to destroy cancer cells. There are two types of stem cell treatment plans available: myeloablative and non-myeloablative. You and your physician will discuss which type of stem cell transplant is best for you.īased on your medical history, test results, and consent, your stem cell physician will identify the treatment plan or clinical research trial that will best treat your specific disease. The type of transplant you will have depends on a number of factors, including your disease, age, overall health, and donor availability. SyngeneicĪ syngeneic stem cell transplant uses the stem cells of your identical twin.Įach type of stem cell transplant involves different procedures, side effects, and risks. ![]() The stem cell donor may be related to you or someone unrelated who is found through a donor registry search such as the National Marrow Donor Program. AllogeneicĪn allogeneic stem cell transplant uses stem cells from someone whose white cell antigens closely match your own. Your transplant physician or nurse will coordinate the stem cell collection process as part of your care. An autologous stem cell transplant uses your own stem cells. ![]()
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